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Chronic Cluster Headache

Dr. Joel R. Saper and Michigan Head•Pain & Neurological Institute (MHNI) are conducting a research study evaluating an investigational medication for the treatment of chronic cluster headaches. Detailed information regarding the study can be found below.

If you are interested in participating, please call (734) 677-6000, option 4 to speak with a research nurse (available between the hours of 8 a.m. and 5 p.m., Monday through Friday) or complete a study application form


Do You Qualify?

If you have been diagnosed with chronic cluster headache and have found preventive and/or acute cluster headache treatments to be inadequate for you, you may be a candidate for the chronic cluster headache study.

To participate in the study you must:

  • Be between 18 and 70 years old
  • Have been diagnosed with cluster headache
  • Suffer from at least 10 cluster attacks per month during baseline
  • Meet other study eligibility criteria

About Cluster Headache

Cluster headache is a very disabling condition. Sufferers can have cluster attacks many times per day, each lasting 15 minutes to 3 hours. Cluster headache is often called 'suicide headache'. The pain caused by cluster attacks is one of the most severe pains known to humans.

Living with cluster headache can be very difficult. When an attack occurs, the intense stabbing pain around one eye, usually accompanied by droopy eyelids with tearing and nasal congestion or runny nose, often results in patients becoming withdrawn and isolating themselves. These repeated attacks leave many sufferers unable to fully participate in life, work, or the activities they enjoy with family and friends.

Since many cluster headache sufferers have gone for years without an accurate diagnosis or adequate treatment, it is important to be seen by a headache specialist.