Migraine Headaches are a painful problem for millions.
Principal investigator Dr. Joel Saper of the renowned Michigan Headache & Neurological Institute (MHNI) is conducting a research study evaluating an investigational medication for the treatment of migraine headaches. To pre-qualify for this study, individuals must:
- Be between 18 and 65 years old
- Experience 2–6 headaches per month
- Experience no more than 14 headache days per month
In general, research studies conducted at MHNI involve individuals who can easily travel to the Institute for regular evaluation and treatment (generally within 100 miles of Ann Arbor, Michigan).
What will happen during this study?
If you qualify, you will receive all study-related care and study medication at no cost, and your migraine condition and overall health will be closely monitored by a team of physicians and study staff. You will be asked to attend all scheduled study visits and record real-time data in an eDiary when you take your study medication.
During the first treatment period, you will treat one migraine headache with either active medication or placebo within a 4-week timeframe. After you treat your first migraine, there is also the possibility of participating in an 8-week extension treatment period with all active medication.
Why is this study being conducted?
Migraine attacks can make it very hard to function at work or home, and may leave you feeling frustrated and hopeless if you can't get them under control. For some people, existing treatments may be ineffective or cause unpleasant side effects. As a result, researchers must constantly search for new ways to treat people with migraine headaches.
Injectable sumatriptan (6 mg) is currently an effective and FDA-approved treatment for acute migraine. In earlier trials, a lower dose of injectable sumatriptan has been shown to have a lower rate of unpleasant side effects than 6 mg injectable sumatriptan. In this study, researchers want to continue to study if injectable sumatriptan is safe and effective at a lower dosage.
What are the benefits of being in this study?
- You will be helping others by contributing to medical research
- You will receive study-required exams and study medication at no cost to you
- The study medication may help relieve your symptoms
- You may be compensated for your time and travel expenses
Any study has risks, which may include side effects related to the study medication. Since the study medication is investigational, there may be risks and side effects that are unknown.
Ready to get started?
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